Dr. Joanna L. Chan explains how skin grafts from a patients own body can repigment areas affected by vitiligo. This surgical option is primarily for patients who fail to respond to topical treatments or phototherapy or have more difficult-to-treat forms of the condition, such as segmental or focal vitiligo. View Video Now. Related PostsIncreased IL-12 [...]
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Dr. Joanna L. Chan: Repigmenting Vitiligo
Increased IL-12 Expression Found in Vitiligo
VIENNA — Interleukin-12 may play a pivotal role in the pathogenesis of vitiligo by promoting melanocyte destruction via cytotoxic immune responses, Marcel Brönimann, M.D., said at the annual meeting of the European Society for Dermatological Research. Interleukin-12 is known to stimulate production of interferon-gamma and other type 1 cytokines and to activate cytotoxic T cells. [...]
Vitiligo May Be First Sign of Localized Scleroderma
“Something unique in our study is that we collected information on body surface area of involvement,” Dr. Gilliam said. “And we had a dermatology perspective rather than a rheumatology perspective.
What is the Endocrine System?
ENDOCRINE AUTOIMMUNITY by Judy Luborsky, Ph.D. Endocrine autoimmunity deals with autoimmune disorders that affect specific endocrine glands. Hashimoto’s thyroiditis (low thyroid function) and Graves’ disease (overactive thyroid function), are among the most commonly occurring endocrine autoimmune diseases. What is the Endocrine System? The endocrine system co-ordinates the body’s physiology and assists in responses to internal [...]
Depigmentation Patterns in Vitiligo
Focal vitiligo is characterized by a few scattered macules. In some cases the depigmenation remains localized to these spots. For others, focal vitiligo can be a manifestation for general vitiligo. Unilateral (segmental vitiligo) In this case the patterns of depigmentatiaon involve small to large areas on one side of one’s body. The patterns of depigmentation [...]
The hair follicle, a pigment cell reservoir
In order for repigmentation to occur in vitiligo, pigment cells must be found in one of these three locations: the hair follicle unit, the border of a vitiligo lesion or unaffected melanocites within depigmented areas. Pigment cells found in the bulge region of the hair follicle are the most important sources for providing immature pigment [...]
How does vitiligo turn hair white?
As social beings humans communicate significantly via their physical appearance, with skin and hair color contributing disproportionately. It is well-accepted that hair growth (a mammal-specific trait) and pigmentation have facilitated evolutionary success in non-human mammals (i.e., via thermal insulation, camouflage, social and sexual communication, and sensory perception) (Wu et al., 2008). However, these traits do not [...]
Basic science of vitiligo- St.Petersburg, Russia- Part 8
On July 6-9, 2011, the Fourth Russian Congress of Dermatovenereology took place in St.Petersburg, Russia. Here is the last of 8 videos of the lectures about vitiligo. httpv://www.youtube.com/user/Vitinomics#p/u/8/uplMAsF2lMI Related PostsNo Related Post
Basic science of vitiligo- St.Petersburg, Russia- Part 8
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On July 6-9, 2011, the Fourth Russian Congress of Dermatovenereology took place in St.Petersburg, Russia. Here is the last of 8 videos of the lectures about vitiligo. httpv://www.youtube.com/user/Vitinomics#p/u/8/uplMAsF2lMI Related PostsNo Related Post
Basic science of vitiligo- St.Petersburg, Russia- Part 7
On July 6-9, 2011, the Fourth Russian Congress of Dermatovenereology took place in St.Petersburg, Russia. Here is the seventh of 8 videos of the lectures about vitiligo. httpv://www.youtube.com/user/Vitinomics#p/u/5/GbF45g5GThI Related PostsNo Related Post